Scientific journal
International Journal of Applied and fundamental research
ISSN 1996-3955
ИФ РИНЦ = 0,593
ISSN 1996-3955
ИФ РИНЦ = 0,593
575 KB
In etiology and pathogenesis of diabetes, atherosclerosis, metabolic syndrome and many other diseases the main role pertains to metabolic disorder. But apparent changes in plasmas concentration of protein, lipids, glucose and other substances are not detected in the first stage of these diseases. This fact may be explained by earlier unknown phenomenon, called adsorption- transport function of erythrocytes (ATFE).. This function take part in quick and selective transfer of substances from blood into tissues. ATFE participate in removal of metabolites, denaturated proteins, atherogenic lipids and some other substances with heightened chemical activity from blood plasma. ATFE take part in return of protein from intersticium, increasing antiedematous potential of blood. Transport of many substances on erythrocytes surface is a changeable and adjustable process. But it allows to determination of initial changes in a metabolism of some substances.
erythrocytes
function
transcapillary exchange
metabolism
disease diagnosis
1. Zbarskyi B., Demin N. Role of erythrocytes in protein exchange // Medicine. – 1949. – 168 p. (rus.).
2. Kikuchi Y., Koyama T. Red blood cell deformability and protein absorption on red blood cell surface. Am. J. Physiol. – 1984. – Vol. 247. – P. 739–747.
3. Müller H., Gramlich F. Die Zusammensetzung des Plasmaproteinfilms an der Oberfläche menschlicher Erythrozyten bei verschiedenen Krankheitsbildern // Blut. – 1964. – B. 10. – S. 135-145.
4. Gareyev R. Transcapillary exchange and lymphformation. – Almaty: Science, 1989. – 142 p. (rus.).
5. Gareyev R. Medicobiological studies, connected to Kazakhstan cosmonauts flights. In: Space research in Kazakhstan. Edit. – Sultangazin U., 2002. – P. 446-460 (rus.).
6. Gareyev R. Second important function of erythrocytes. In: Physiological fundamentals of healthy life-style: materials of 4th Kazakhstani physiologist’s congress. – Astana, 1999. – P. 111-115 (rus.).
7. Gareyev R. Concept of absorptive transport functions of erythrocytes. In: Materials of 5th Kazakhstani physiologist’s congress. – Karaganda, 2003. – P. 75-79 (rus.).
8. Kassirskyi I., Alexeyev G. Clinic hematology // Medicine. – M., 1970. – 800 p. (rus.).
9. Gareyev R. Terms and indexes of adsorption – transport function of erythrocytes. In: International science conference devoted to 10 years of Kazakhstan. – Almaty, 2001. – P. 80-81(rus.).
10. Gareyev R. Glucose adsorption on erythrocytes and initial form of diabetes. Pavlov`s XIX physiologist’s congress: Russian physiological magazine. – 2004. – part 2, V. 90, № 8. – p. 134 (rus.).
11. Gareyev R. Perspective research tendency for clinic. In: Article collection for 100 years of Polosuhin A. – Almaty, Galim, 2001. – P. 135-140 (rus).
12. Gareyev R. Blood-tissue-lymphatic metabolism in aetiology-pathogenesis of diseases. In: Materials of international conference of cardiology Research Institute «Present problems of theoretical and clinic lymphology; epidemiology, diagnostic and treatment of metabolic syndrome»: Materials of international conference of cardiology Research Institute. – Almaty, 2003. – P. 52-57 (rus.).